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perinatal_jaundice (intermediate (1 day - 2 weeks) (Crigler-Najjar…
perinatal_jaundice
intermediate (1 day - 2 weeks)
Crigler-Najjar syndrome
G6PD deficiency
polycythemia, bruising
physiological jaundice, breastmilk jaundice, dehydation
infection (UTI)
early (1 day)
congenital infection
spherocytosis
G6PD, pyruvate kinase
Rhesus isoimmunization
Rh- mother attack Rh+ more and more
first pregnancy at labour: Rh- mother meet Rh+ baby
Rh- mother Rh+ father
ABO incompatibility
Group O mother: anti-A(B) to Group A baby
IgG antibody: small: v across palcenta
IgM antibody: big: x across placenta
physiological jaundice
unconjugated to conjugated (glucuronsyltransferase) not yet efficient
short life span
many hemoglobin
prolonged (2 weeks)
conjugated (direct bilirubin)
(pale stool, HIDA scan) biliary atresia
choledochal cyst
neonatal hepatitis
unconjugated
pyloric stenosis
low Na low K low Cl
metabolic alkalosis
dehydration (but)
hypothyroidism
infection (UTI)
G6PD deficiency