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gihep 11: digestion + absorption of protein + carbs (ii) (transport across…
gihep 11: digestion + absorption of protein + carbs (ii)
carb digestion
1) mouth
mechanical (chewing)
salivary alpha amylase hydrolyses random alpha(1->4) bonds
inactivated by low pH of stomach
2) SI
endoglycosidases
pancreatic amylase
brush border enzymes
disaccharisases
sucrase
lactase
trehalase (converts trehalose to glucose)
oligosaccharidases
transport across basolateral membrane
by facilitated diffusion + cotransport into interstitial fluid
transported to liver via portal system
glutamate + aspartate NOT transported out of enterocyte
utilised for energy
Monosacc absorption
(a) passive diffusion (slow)
(b) membrane-associated transporters
SGLT1
Na+ dependent glucose channel
down conc gradient
GLUT5
Na/K ATPase pump (provides energy)