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Sepsis and Shock (Sepsis Definition (Sepsis II (Infection + SIRS = Sepsis,…
Sepsis and Shock
Sepsis Definition
Sepsis II
Infection + SIRS = Sepsis
SIRS=2 or more of following
HR over 90
WBC over 12 or under 4
temp over 38 or under 36
RR over 20
Sepsis + organ
dysfunction=severe sepsis
Severe sepsis + shock= septic shock
Sepis III
Infection + organ
dysfunction= sepsis
Sepsis + pressors
& lactate=septic shock
Shock
clinical indicators
MAP
Most important
designates amount of blood perfusing organs
1/3 SBP + 2/3 DBP
Serum lactate
Cellular Ischemia
End-organ dysfunction
encephalopathy
Oliguria
Causes
Distributive
Can't squeeze vessels
Septic
Anaphylactic
Spinal
Metabolic
Endocrine
Cardiogenic
Heart can't squeeze
Ischemia
Cardiomypathy
PE
Tension PTX
Tamponade
Hypovolemic
Not enough fluid to squeeze
Hemorrhagic
Other
Sources
Neonatal
Bacteremia
Group B strep
E. Coli
H. Influenzae
S. Aureus
S. Pnemoniae
Listeria
Meningitis
Pulmonary
Everyone Else
Respiratory
Urinary
Bacteremia
E. Coli, Klebsiela, Enterobacter
S. Auereus
Fungi
Pseudomonas
REgional Bacteria
Viruses
Abdominal
Skin
CNS