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Pharmacology of Thyroid and Parathyroid (Thyroid (Hyperthyroidism…
Pharmacology of Thyroid and Parathyroid
Thyroid
Hyperthyroidism
Treatment
Thioureylenes
Propylthiouracil
Carbimazole
Methimazle
Inhibits the enzyme thyroperoxidase
131 Iodine
Reduce the levels of thyroid hormone
Emits gama and beta rays that exert cytotoxic effect.
Oral administration
Half-life 8 days
effects take up to 2 weeks
Surgery
Total thyroidectamy
Subtotal thyroidectomy
Symptoms
Intolerance to heat
Tachycardia
weight loss
Muscle wasting
Causes
Grave's disease
Toxic Thyroid Adonema
Toxic multinodular goiter
AIDS
Diagnosis
123 Iodine radioisotope for nuclear imaging
Hypothyroidism
Thyroxine
Adjunctive therapy (to assist primary therapy)
Propranolol
Guanethidine
Parathyroid
Adjunctive therapy
NSAID
Ibuprofen
Piroicam
Diclofenac
Hypoparathyroidism
Calcium salts
Vitamin D
Teriparatide
Hyperparathyroidism
Bisphosphonates
Risedronate
Alendronate
Calcimimetics
Cinacalcet
Calcitonin