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Chapter 19 - Gram Positive Bacilli of Medical Importance (Gram Positive…
Chapter 19 - Gram Positive Bacilli of Medical Importance
Gram positive rods
Endosporeformers
Bacillus Anthracis - mostly live in soil
Cutaneous
Pulmonary
Gastrointestinal
aerobic and catalase positive
Bacillus Cereus - lives airborne and in dust
food intoxication lasting approx 24 hours, no treatment
Clostridium
Clostridium Perfringens
gas gangrene/myonecrosis
myonecrosis - more destructive and diffuses into nearby tissues.
anaerobic cellulitis - infection localized and does not spread
leads to Clostridial gastroenteritis - food poisening if ingested
Clostridium Difficile
antibiotic associated colitis
Clostridium Tetani
tetanus/lockjaw
Clostridial Botulinim
improper canned foods
Infant botulism
Wound botulism
Also Gram positive Rods
Non-spore forming rods
Listeria monocytogenes
cause lysteriosis associated with dairy , meat. and poultry
Erysipelothrix rhusiopathiae
lives in pigs and causes erysiopeloid common in ppl who handle animals. Characterized by inflammed red sores at portals of entry on skin.
Gram Positive Non Spore Forming Irregular Shaped Bacilli
Mycobacterium *
Identified as Acid Fast Bacilli AFB
Mycobacterium tuberculosis --> causing tuberculosis
Primary Pulmonary Infection
Secondary TB
Disseminated extrapulmonary TB
Mycobacterium Lerae
causes leprosy in 2 forms
Tuberculoid - superficial, dmaage to peripheral nerves, feather test
Lepromatous
disfigurement, loss of pain receptors
Mycobacterium Other Than TB (MOTT)
MAC causes disseminated disease of AIDS patient
M. Marinum causes swimming pool granuloma
Actinomyces
proprionibacterium
Anaerobic - associated with acne,
Nocardia *
Corynebacterium *
Corynebacterium Diphtheria
aerobic, spread by droplets, with 2 stages of disease
local upper respiratory tract infection
Diptherotoxin - exotoxin released that targets the heart and nerves