As the composition of collagen in the bone is not correct, even when there are no fractures there will be other problems connected to the condition; such as the ligaments stretch more easily, joint hypermobility can significantly affect the quality of life as it results in fatigue of many muscle groups. As a result, the mobility and performance of ordinary tasks of everyday living are impaired. Other symptoms can be; hearing loss, fatigue, joint laxity, curved bones, scoliosis, blue sclerae, dentinogenesis imperfecta (brittle teeth), and short stature amongst other medical problems.