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Standard Amino Acid (Neutral polar (Serine, Threonine, Tyrosine, (Contain…
Standard Amino Acid
Neutral polar
Serine, Threonine, Tyrosine,
Contain polar OH group
Participate in hydrogen bonding
-OH groups of Serine & threonine - points for attaching carbohydrates
Asparagine,Glutamine
Amide derivative
Amide functional group highly polar
Acidic
Aspartate, Glutamate
Carboxylate group as a side chain
Negatively charged at physiological pH
Neutral non-polar
Glycine ,Alanine,Valine, Leucine, Isoleucine, Phenylalanine, Tryptophan, Methionine, Cysteine,Proline
R groups do not bear +/- charge
R group interact poorly with water
Maintaining three-dimensional structure of protein
Basic
Lysine, Arginine, Histidine
Positively charge at physiological pH
Histidine - weak base
Partially ionised at pH 7
Guanidino group of Arginine
Permanently protonated at physiological pH
Does not function in acid base reaction