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Anti-epileptic Drugs (Secondary anti-epileptic :pencil2: (Lamotrigine…

- - - - Due to increased androgen secretion
    - - Can be treated with folate therapy
    - - Associated with formation of epoxide metabolite
- - - - Chronic pain that affects the trigeminal neurone, which carry sensations from face to brain
  - - - Stupor (near-unconsciousness)
      - Coma
      - Hyperirritabolity
      - Convulsion
      - Respiratory depression
    - - Use with caution in elderly patients with cardiac disease (like heart failure)
- - - - Because of its low toxicity and less sedative effect
- - - - Can be treated with folate therapy
    - - Can be treated with Vitamin D therapy
- - - - Also activates hyperpolarizing K+ channels and GABA-A receptor
      - Reduces activation of glutamate receptors
    - - used cautiously in patients with kidney stone
    - - used in GTC and focal epilepsy
      - Also used in refractory cases