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ENDOMETRIOSIS (COMMON PRESENTING SYMPTOMS: (ovulation pain, cyclical or…
ENDOMETRIOSIS
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EXAMINATION
thickened pelvic ligaments, particularly uterosacral ligaments which may be nodular
on speculum exam, blue nodules in posterior vaginal fornix
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Transvaginal US can detect gross endometriosis involving ovaries (endometriomas or chocolate cysts) and occassionally rectum
MRI can delineate the extent of active endometriosis lesions greater than 1cm in diameter in deep tissue e.g. rectovaginal septum
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MANAGEMENT
SURGICAL
when continued fertility is required, conservative surgery is appropriate - LAPARASCOPIC EXCISION OR ABLATION OF ENDOMETRIOSIS DEPOSITS
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MEDICAL
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or a pseudo menopause
GnRH anslogue [SECOND LINE] - nasal spray/implant/injection USE 4-6MONTHS AND HAVE ADD BACK HRT TO AVOID MENOPAUSE EFFECTS
in turn the analogue causes a reduction in gonadotrophin release, hence ovarian steroid secretion
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DANAZOL RARELY USED - combines androgenic and anti-oestrogenic activity and inhibit pituitary gonadotrophins - tonnes of SE
LEVONORGESTREL-RELEASING INTRAUTERINE SYSTEM (MIRENA) - reduces endometriosis assoc pain. Useful in prevention after surgery
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Chronic pelvic pain - constant or intermittent pain in lower abdomen or pelvis of at least 6 months not assoc with preg
CAUSES OF CHRONIC PELVIC PAIN:
- endometriosis
- adenomyosis
- ovarian cysts
- scar tissue
- adhesions
- IBS
- interstitial cystitis
- chronic pelvic infection
- MSK
- nerve entrapment
ENDOMETRIOSIS- endometrial like tissue outside of the uterus = induces a chronic inflammatory reaction
usually lies within peritoneal cavity and predominantly in pelvis - commonly uterosacral ligaments behind the uterus
rarely in distant sites:
- umbilicus
- abdo scars
- perineal scars
- pleural cavity
- nasal mucosa
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CHRONIC PELVIC PAIN presents in primary care as:
depending on the severity of the disease, adhesions and fibrosis may distort bowel/bladder/ureters and other neighbouring viscera --> lead to chronic problems