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Lec 2.1 - Water & Osmosis (Osmosis - Move Water (Tonics (HYPERosmotic,…
Lec 2.1 - Water & Osmosis
Osmosis - Move Water
Membrane
Concentration gradient
To highest concentration
Tonics
HYPERosmotic
Sol > Cell
Out
ISOosmotic
Sol = Cell
None
HYPOosmotic
Sol < Cell
In
Tonicity
Cell shape
HYPERtonic
Shrinks
ISOtonic
Same
HYPOtonic
Swells
Body
Homeostasis
Balance (water & solutes)
ECF
#
Interstitial fluid
Tissue
Plasma
Lymph
Solute
High Na+, Cl-, Ca2+, HC03-
ICF
Solute
High K+, PO43-, protein
Osmolarity (NEEDS MORE WORK)
Mole
Molarity
Body fluid
300 mOsmols/L = 0.3 Osmols/L
Osmotic Pressure
High osmolarity
High osmotic pressure
Tonicity
Membrane
Transport
Signalling
DIffusion
Passive
Diffusion
Channel Proteins
Selective
Gated
Rate
Not direction
Electrochemical gradient
Carrier mediated
Large polar molecules
Bind
Transported
Specific
Saturated
Max rate
Competitive
Facilitated Diffusion
Bind
Change shape
Active
Secondary
Expend ATP
Homeostasis
Vesicular
Macromolecules
Primary
"Uphill"
Requires energy
Transmembrane potential
Pumps
Calcium
Hydrogen
Sodium-Potassium
Molecules
Polar
Low permeability
Non-Polar
High permeability
More lipid soluable
