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Epidermolysis Bullosa (Dystrophic EB (Histo (Defective attachment of BM to…
Epidermolysis Bullosa
Dystrophic EB
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Complications such as poor intake, consipation, urethral scarring, phimosis
Increased SCC risk, difficult to surgically treat
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Junctional EB
AR, mutation depends on type
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Blistering at birth, usually mouth/nose
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EB simplex
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Histo
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Positive staining for BM components in BASE of split (GB3, Laminin 5, type 4 collagen)