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Устойчивость к бактериоцинам гр+ бактерий Resistance to bacteriocins…

- - - - orphan immunity genes
    - - nisinase, which degrades nisin
    - - changes in electrostaic interactions between the bacter-
        iocin and the cell surface in the presence of high ion
        concentrations
      - cell morphology may change
        due to increased osmolarity of the growth medium, leading
        toc hanges in the cell envelope
      - Nisin resistance of L.monocytogenes has also been associated
        with acid stress response
        
        glutamate decarboxylase system is
        considered the most important system employed by this
        species to with stand low pH stress
    - - тейхоевые и липотейхоевые кислоты
        
        их основа сильно заряжена за счет депротонированных фосфатных групп
        
        эстерификация основы Д-аланином уменьшает отрицательный заряд при помощи втраивания основных аминогрупп