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Endometrial Pathology (ENDOMETRIOSIS Non Neoplastic Endometrium like…
Endometrial Pathology
Polyp
Painless Abnormal Uterine Bleeding
ADENOMYOSIS
Extension of Endometrium into Myometrium
BASAL LAYER HYPERPLASIA of Endometrium
Hx
Dysmenorrhea & MENORRHAGIA
GLOBULAR Uterus
ASHERMAN Syndrome
ADHESION / FIBROSIS of Endometrium
Hx
Fertility
RECURRENT pregnancy LOSS
Abnormal uterine bleeding
PELVIC Pain
Cause
DILATON & CURETTAGE of Uterine Cavity
LEIOMYOMA
AFRICAN AMERICAN Female
Dx
WHORLED Pattern of Smooth Muscle Bundles
WELL DEMARCATED Borders
CHARACHTERISTICS
ESTROGEN SENSITIVE
Size in Pregnancy
in Menopause
PEAK occurrence at 20-40 Years
Hx
ABNormal Uterine Bleeding
IRON DEF ANEMIA
Hyperplasia
EXCESS ESTROGEN
NUCLEAR ATYPIA
Endometrial Carcinoma
POSTMENOPAUSAL Vaginal Bleeding
RISk Factors
ANOVULATORY Cycles
HRT ( Hormone Replacement Therapy )
POLYCYSTIC Ovarian Syndrome
ENDOMETRIAL CARCINOMA
Most Common Gynecologic Malignancy
55--65 Years
Hx
Vaginal Bleeding
RISK Factors
PROLONGED USE OF ESTROGEN WITHOUT PROGESTIN
LYNCH Syndrome
LaATE Menopause
EARLY Menarche
Obestity
DM
HTN
ENDOMETRITIS
Inflammation by Bacterial Flora
RX
GENTAMICIN + CLINDAMYCIN +/- AMPICILLIN
Cause
REATINED PRODUCTS OF CONCEPTION after Delivery
IUD
CHRONIC Endometritis
PLASMA CELLS
ENDOMETRIOSIS
Non Neoplastic Endometrium like Gland / Stroma outside Endometrium cavity
SITES
OVARY ( Most Common )
BLOOD filled CHOCOLATE CYSTS
Pelvis & Perineum
Hx
CYCLIC PELVIC PAIN & Bleeding
DYSCHEZIA ( Pain with DEFECATION )
DYSMENORRHEA
DYSPAREUNIA
Rx
NSAIDS
CONTINUOUS OCP
PROGESTIN
GnRH Agonists
DANAZOL
LAPROSCOPIC REMOVAL
Pathology
Retrograde flow to Ovary
Transformation of Multipotet Cells
Transportation of Endometrial tissue via Lymphatic System