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Anti-cancer Drugs (Problems with
anti-cancer
chemotheraphy (sever side…
Anti-cancer Drugs
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Chemotherapeutic drugs
Alkylating agents
originated from mustard gas, which was
observed to inhibit white blood cell proliferation
crosslink DNA bases (especially Guanine),
inhibiting DNA replication
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Anti-metabolites
modified natural metabolites, which are supposed to be incorporated to cancer cells and inhibit their proliferation
Methotrexate
substitutes for folic acid,
inhibiting nucleotide production
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Drug Targets
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Chemotheraphy is most often used with other
modalities of therapy, such as Surgery and Radiation
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