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Bone Tumors (Long Bone (Metaphysis (Osteosarcoma (Mostly males less than…

- - - - 20-40 yo
        Epiphysis of long bones often in knee
        Benign but locally aggressive
        Neoplastic mononuclear cells that express RANKL and osteoclast-like multinucleated cells
        Soap bubble on x-ray
        
        Benign
  - - - Mostly males less than 20 yo
        Common primary bone cancer, but can also be secondary
        On metaphysis of long bones often in knee
        Malignant osteoblasts
        Painful
        Codman triangle - triangle shaped tumor because periosteum holds it to that shape
        
        Malignant
    - - Males Less than 25 yo
        Metaphysis of long bones
        Lateral bony projections of growth plates covered by cartilage caps
        
        Benign
  - - - Mostly males less than 25 yo
        Cortex of long bones
        Bone pain relieved by NSAIDs
        Bone mass with radiolucent osteoid core
        
        Benign
    - - Mostly Caucasian boys less than 15 yo
        Diaphysis of long bones, pelvis, and flat bones
        Neuroectodermal cells that resemble lymphocytes
        T(11;22) fusion EWS-FLI1
        Onion skin periosteum
        
        Malignant
- - - - Malignant
  - - - Malignant
- - - - Malignant
  - - - Benign
- - - - Benign
- - - - Benign