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Myasthenia Gravis (Clinical signs and symptoms (History of painless muscle…
Myasthenia Gravis
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Diagnostic tests
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Spirometry: Decreased Vc, MIP/NIF, MEP
Respiratory Management
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Mechanical ventilation
Vc < 1.0 or < 15 mL/Kg, MIP/NIF < -25 cmH2O, MEP < 40 cmH2O
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Respiratory failure, aspiration pneumonia
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Etiology
Autoimmune disease in which excessive anti-acetylcholine receptor antibodiy blocks the acetylcholine receptors at the myoneural junction with progressive DESCENDING muscle weakness
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