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Ulcerative Colitis (Diagnosis (Liver biochemistry may be abnormal, Will…
Ulcerative Colitis
Diagnosis
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Colonoscopy a Gold Standard with mucosal biopsy. Will show goblet cell depletion, crypt abscesses and mucosal ulcers
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Signs/ Symptoms
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Acute exacerbation will have bloody diarrhoea. Happens a lot at night. very disabling and causes incontience
Complications
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Colon- blood loss, perforation, colorectal cancer
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Eyes: iritis , uveitis and episcleritis
Epidemiology
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Highest incidence in N Europe, UK or N America
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Extra intestinal signs: there will be an increase in mouth ulcers, amyloidosis, clubbing and erthema nodusum