Exercise metabolism & Energy expenditure

Exercise metabolism

Substrates

Energy pathways

Rates & yields

CHO

FAT

PROTEIN

ATP-PC

Glycolytic

Oxidative

Energy expenditure

Performance

Health

Demands of exercise OR performance?

Energy expenditure > Energy intake = negative energy balance

Assess

Energy ex

Methods

Measure

Substrate metabolism efficiency

Heat production increases with energy production (Direct Calorimetry; measuring heat)

Direct calorimetry

Pros & cons

Indirect calorimetry

Indirect as it does not measure heat production

Limitations

Isotopic measurements

Isotope: element with atypical atomic weight


13C, 2H (deuterium) common isotopes for studying energy metabolism

O2 and CO2 Measurements


VO2: volume of O2 consumed per minute


VCO2: volume of CO2 produced per minute

Haldane transformation

V̇ of inspired O2 may not = V̇ of expired CO2

V̇ of inspired N2 = V̇ of expired N2

Respiratory Exchange Ratio

O2 usage to metabolize 1 molecule Fat or CHO is dependent on carbon content

O2 usage during metabolism depends on type of fuel being oxidized

Respiratory exchange ratio (RER)

RER for 1 molecule glucose = 1.0

RER for 1 molecule palmitic acid = 0.70

Predicts substrate use, kilocalories/O2 efficiency

Energy Expenditure at Rest and During Exercise # #

Metabolic rate: rate of energy use by body

Based on whole-body O2 consumption (VO2) and corresponding caloric equivalent

Basal Metabolic Rate

(BMR): rate of energy expenditure at rest

Minimum energy requirement for living

Resting Metabolic Rate

(RMR)

Total daily metabolic activity

Metabolic Rate during Submaximal Exercise

Increased metabolism increases directly relative to exercise intensity

More recent evidence suggests VO2 response at higher work rates.

Prediction of BMR

Harris-Benedict (1919) Males: 66.47+13.75(wt)+5(ht)-6.76(age)
Females: 655.1+9.56(wt)+1.85(ht)-4.68(age)

Cunningham (1980) 9.99(wt)+22(LBM)

many more, all are estimates

Predicting RMR

BW x 1.0 x 24hr – Men
BW x 0.9 x 24hr – Women
….and others.

Metabolic Equivalent (METS)

Activity Diary

Tues Night 6pm – Weds Night 6pm
Time
Activity
METs

SUMMARY/LAB

Measure RMR
Measure / Estimate Energy Expenditure
Check Activity Diaries