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Guillain-Barre Syndrome (Clinical Signs & Symptoms (History of Recent…
Guillain-Barre Syndrome
Etiology
Following a viral or bacterial infections, especially cytomegalovirus (CMV) and Campylobacter Jejuni (diarrhea)
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Pathophysiology
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Muscle paralysis then spreads upward and affects the lungs by insufficient negative pressure generated and inability to exert a cough
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Diagnostic Tests
Cerebrospinal Fluid (High protein, low WBC; also called albuminocytologic dissociation of the spinal fluid)
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Decreased VC, MIP/NIF, MEP for spirometry
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Respiratory Management
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Intubation if: VC <1L or <15ml/kg, MIP/NIF <-25 MEP <40, Inability to cough, swallow and protect the airway, ABG evidence of respiratory failure