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disorders of fluid regulation (diabetes insipidus (types (neurogenic DI:…
disorders of fluid regulation
SIADH
(syndromes of inappropriate antidiuretic hormone secretion)
excess ADH (vasopressin) secretion
causes
septic shock
CNS lesions
cirrhosis
neoplasm
congestive heart failure
effects on the body
water retention
sodium excretion
(b/c the body responds to water retention by decreasing aldosterone which allows more Na+ to be excreted into the urine)
hyponatremia
hypoosmolality
diabetes insipidus
types
neurogenic DI:
defect in synthesis and release of ADH
nephrogenic DI:
insensitivity of the kidney to ADH
characterized by polyuria and polydipsia
treatment is synthetic vasopressin analogs
can be caused by damage to the hypothalamus from tumors, meningitis, and head injury