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SHOCK (2) (VULNERABLE SITES: (LOW FLOW SITES (2ND CAPILLARY BEDS (ANTERIOR…
SHOCK (2)
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KIDNEY
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RENIN ANGIOTENSIN SYSTEM
THIS AFFECTS ONLY PCT ( VULNERABLE TO SHOCK DUE TO 2ND CAPILLARY BED) CAUSING ACUTE TUBULAR NECROSIS
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OUTCOME
ATN=TUBULAR CELLS ARE LABILE & IF PATIENT SURVIVES SHOCK, TUBULES WILL RECOVER FUNCTION
ACN=PODOCYTES ARE PERMANENT CELLS, SO GLOMERULUS CAN'T REGENERATE, IF PATIENT SURVIVES A FIBROUS SCAR WILL FORM & WILL NEED LIFETIME DIALYSIS.