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Pierce ch 5: Marijuana (physical effects (may adversly affect reproductive…
Pierce ch 5: Marijuana
most common illicit drug
pharmacology
Delta-9-tetrahydrocannabinol (THC) psychoactive element
concentrations peak in 10-15 min
effects last 2-3 hours
THC metalpolized through cytochrome P450system
1/3 in pee and 2/3 in :poop:
supresses GABA producing cells and learning process called long therm potentiation
physical effects
chronic use may lead to pulmonary immune function
adversly affects cardiovascular system
changes blood pressure
increases mycardial demand
decreases mycardial oxygen
subseqently increases angina
may adversly affect reproductive system
decrease of testosterone level
cause testicular atrophy
lead to gyneconmastia
reduce fertility
cause birth defects
change of interest in personal achievement called amotivational syndrome
cognitive effects
decreased
planning
organizing
problem solving
decision making
memory
control of emotions and behavior
residual effects of cannabis 7-20 hours after use imapirs
decision making
impaired attention (possibly)
concentration
inhibition
impoulsivity
verbal fluency