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Honeybee Apis mellifera (2006, Nature) (Gene content and the proteome…
Honeybee Apis mellifera (2006, Nature)
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Genome organization
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Sequence characteristics: low GC content, over-represented CpG
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Functional categories
Caste, reproduction and ageing
Caste development: oxidoreductases, hydrolases
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Ion channels, neurotransmitters and other signalling molecules: neuropeptides/hormone GPCRs
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Circadian rhythms: cryptochrome (Cry), timeless (Tim), clock
(Clk) and cycle (Cyc)
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Anti-xenobiotic defence mechanisms: carboxylesterase (CCE), cytochrome P450 and GST
Gene regulation
RNA interference: Dicer, Drosha homologue, argonaute 1 and 2, double-stranded RNA binding proteins—R2D2, Pasha and Loquacious
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Development
Sex determination, lack of dosage compensation and male meiosis
Homeobox genes: PAX, POU, LIM and other domains
Signalling pathways: Wnt, Hedgehog, TGF-beta, receptor tyrosine kinase, Notch, JAK/STAT, nuclear hormone
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