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AUTOMATION (Automation in Clinical Biochemistry (((Automation provides a…
AUTOMATION
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CENTRIFUGAL ANALYSER
This type,the reaction takes place in the rotor of a centrifuge. The system consist of:
1) Rotor Disc
-This is a disc which can be spun at a high speed by vertically mounted electric motor. The upper surface of the disc has concentric rings of specially designed cavities, forming 3-4 discrete wells along the radius.
2) Photometer
-A photometer is mounted near the periphery of the rotor disc in such a way that its light path is parallel to the axis of rotation(vertical).
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CONTINUOUS FLOW SYSTEMS
- Sampler -
this consists of circular tray with separate cups for samples along its periphery. The amount of sample or wash solution aspirated is regulated by an electrical timing device which controls the pumping rate and dwell time of the probe in each cup. A bar coding system is used for specimen identification.
- Proportionating pump - This module represents the use of different sizes of pipettes to add varying volumes of reagents to the reaction mixture in manual methods. A peristaltic action is produced by a series of rollers passing along a set of plastic tubes parallel to each other.
- Manifold - The manifold may have 3 or more submodules which can removes protein, mix reagent and incubate at the desired temperature.
-The common submodules are the dialyser, mixing coils and incubator bath.
- Colorimeter - The colorimeter continuously measures the absorbance of the solution which is passing through the flow cell, at a given wavelength.
- Recorder - The light transmitted by the coloured solution causes a voltage change in the Photodetecter. This voltage is constantly measured and recorded by the recorder.