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Immunology & Immune System (Introduction to IMMUNE SYSTEM (4…
Immunology & Immune System
Introduction to IMMUNE SYSTEM
4 characteristics
Memory
Reaction to subsequent exposure is stronger
Immune Effector Functions
Destructive capacity
Complement system
Antibodies
White blood cells
Recognition
Capacity to detect foreign & self antigen
Regulation
Ability to self-regulate
Failure leads to Allergy & Auntoimmune
Lymphatic System
Primary Function:
To transport
lymph
throughout body
Fluid containing infection-fighting WBC
Remove toxins/waste/unwanted materials from body
Structures
Bone marrow
Production site of WBC
Thymus
Storage and maturation site of lymphocytes (WBC)
Lymph nodes
Filtering foreign and cancer substances
Immune Cells
Lymphocytes
T cell
Secretes cytokines
Receptor: embedded in membrane
NK cell
Release lytic granules
B cell
Secretes antibodies (into extracellular) and APC
Myeloid Cells
Neutrophil
Phagocytosis and bactericidal mechanisms activation
Eosinophil
Killing of antibody-coated parasites
Denditric
Antigen uptake at peripheral tissue & APC
Basophil
Unknown
Macrophage
Phagocytosis and APC
Mast cell
Release histamine granules