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(Gastro Plus Simulations (Actual Vs Predicted [Shape, Cmax:AUC, Tmax,…

- - - - Hydrophobic Solvents
      - Hydrophilic Solvents
  - - - Wet
      - Dry
    - - Jet Mill
      - Ball Mill
  - - - 1
      - 2
      - 4.5
      - 6.5
      - FeSSIF
    - - Kinetic
      - Saturation
      - Intrinsic
  - - - Method of API extraction from formulation
      - Sonication Time
      - No of Frames
      - No of particles counted
      - Interference from other excipients
      - No of internal validation formulation used
    - - Malvern
      - Raman
      - Hot Stage
- - - - Check for Enterohepatic Circulation
- - - - Gut Wall
      - First Pass
      - Post Systemic
        
        Oxidative
        
        Conjugation
  - - - Gut Wall
      - First Pass
      - Post Systemic
        
        Oxidative
        
        Conjugation
- - - - Composition of solution
      - Time Points adequate to capture Cmax
- - - - Impact of week granules on better BA under Fed state