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61. Etiology and pathogenesis of liver diseases. Types of liver…

- - - - functional abnormalities in renal salt and water homeostasis
      - (+) risk of GI haemorrhage
- - - - (-) bile flow
        
        Hyperlipidemia
  - - - net elevation of toxins in blood e.g. ammonia
        
        hepatic encephalopathy
  - - - enzymatic conversion if androgens to estrogen
        
        (+) blood oestrogen
        
        altered hepatocyte protein synthesis
        
        altered P450 activity
        
        feminisation in male patients- gonadal and pituitary suppression