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cytoskeleton (MF (func (transportation (cell, vesicles), cytokinesis (form…
cytoskeleton
MF
EM
thin ED filament
polymerization
G-actin monomers
polymerize to form F.actin
polymerisation occur more rapid at + end
depolymerization occur more rapid at - end
polarisation
(+) end
(-) end
organization
parallel (bundles)
anastomosing (network)
func
transportation
cell
vesicles
maint. cell shape
cytokinesis
form contractile ring)
muscle contraction
forming MV
attachment to ECM
7nm diameter
IF
10nm
EM
ED filaments
high tensile strength
constructed like woven robes
func
structural role
attach to desmosomes
provide mechanical stability (resist pulling forces exerted on cells)
types
1 & 2 (acidic & basic)
EC
3
vimentin
fibroblast
leukocytes
endothelial
desmin
MC
GFAP
NC (astrocytes)
peripherin
peripheral NF
4 (neurofilament)
NC
5 (lamin)
line INE
MICROTUBULES
25nm
MTOCs
centrosome
LM
2 perpendicular centrioles (rodes)
surrounded by centrosphere
EM
9 triplets of MT (1= 13 PT + 2= 10 PF)
func
form
cilia & flagella
EX
flagella of spermatozoa
cilia of tracheobronchial & fallobian epithelium
structure
basal body
repl. of centrioles
9 triplets of MT
present in Apical cytoplasm
shaft (axoneme)
9 doublets of MT with a central pair of singlets (20 MT)
rootlets
anchor the cilia into CP
centriole
mitotic spindle
transport
MTAP
dynein
move organelle or vesicle t/w cell center (- end)
kinesin
move organelle or vesicle t/w cell periphery (+ end)
EM
ED tubules
polymerisation
a- & b- tubulin dimers
polymerise to form protofilament
13 of them form 1 MT
func
maint. cell shape
cellular motion
organelles
vesicles
regions of the cell
the whole cell