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Regulation of gene expression (Prokaryotes) (Regulation of gene expression…
Regulation of gene expression (Prokaryotes)
Transcription Attenuation
Trp Operon
Trp levels are low/ tRNA Trp not abundant
allows transcription
tRNA Trp is high
No transcription
Lac Operon
Lactose (absent)
No Trascription
Lactose (present)
Activation of Transcription(depending on glucose level)
CRP (CAP)
Activation of Transcription
Structural Motif
Zinc Finger
Leucine Zipper
Helix-turn-helix
Basic helix-loop-helix
Regulation of Bacterial mRNA
In Trans
small RNA (sRNA)
OxyS + protein Hfq
(inhibits translation)
DsrA + Protein Hfq
(promotes translation)
In Cis
Riboswitches
Regulation of gene expression (Eukaryotes)
Assembly of Transcription Initiation Complex
Methylation of DNA
Covalent modification of histones
Histone Methyltransferase Reaction
Histone Acetyltransferase Reaction
Eukaryotic promoters and regulatory proteins
Nucleosome can be restructed by specific protein complexes
Hormones binding to receptors
Type 2 Hormone receptor
Type 1 Hormone receptor