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cell membrane (func (selective permeability (small, nonpolar, fat soluble)…

- - - - subs
        
        bact
        
        cell debris
      - selective
      - phagocytes
        
        WBC
        
        MP
      - CM extend —> pseudopedia
      - engulf particle & form phagosome
    - - nonselective
      - subs
        
        fluid cont. ions & S.Prot
      - cell
        
        endothelial BV
      - pinocytotic vesicles are smooth & small
    - - HSP
      - subs
        
        LDLP
        
        horm
      - Clathrin-coated pits invaginate
        
        clathrin is recycled
        
        Spinous small coated vesicles
  - - - transport vesicles fuse W/ CM
      - e.g, Plasma & fibroblasts
    - - Memb bounded secretory granules store products in apical cytoplasm
      - hormonal or neural stimulation
      - vesicle move & fuse W/PM
      - e.g, gastic mucous memb & acinar cells of Panc
- - - - LM
        
        thin dense line (8-10 nm)
      - HM
        
        trilaminar str (unit memb)
        
        outer ED line (outer leaflet)
        
        inner ED line (inner leaflet)
        
        middle EL zone
        
        expl
        
        osmium deposit in HPL heads ->
        
        HPB tails unstained ->
  - - - phospholipid bilayer
        
        hydrophilic, polar heads
        
        faces CP & ECM
        
        comp
        
        phosphate gr
        
        nitrogenous comp
        
        glycerol
        
        2 hydrophobic, nonpolar FAT
        
        within the lipid bilayer
      - cholestrol
        
        stability
        
        flexibility
        
        reg. memb fluidity
        
        not too rigid
        
        not too fluid
    - - integral (TMP)
        
        pumbs
        
        channels
        
        enzymes
        
        ATP synt - IMM
        
        adhesion molucules
        
        linker (CS to ECM)
        
        cell to cell junc
        
        receptors
        
        carriers
      - peripheral
        
        not embeded
        
        loose association with integral memb prot
        
        U on CS
    - - types
        
        GP
        
        GL
      - func
        
        br. saccharides ext from S to form coat
        
        protect
        
        identity labels
        
        cell adhesion
        
        receptors
    - - sea of lipids
      - icebergs of proteins floating
      - dynamic str
        
        prot displacement restricted
        
        attached to cytoske
        
        occluding junc