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Evaluate the view that Schizophrenia has a stronger biological cause. (12…
Evaluate the view that Schizophrenia has a stronger biological cause. (12 marks)
A01
Dopamine hypothesis (Carlsson)
Too much dopamine causes schizophrenia
When lots of dopamine is released
Not being broken down by enzymes
Too many D2 receptors
D2 receptors are too sensitive
Mesolimbic pathway = positive symptoms
Mesocortic pathway = negative symptoms
A03 +
Randrup and Munkvad
Study on rats
Amphetamine
Increased dopamine
A03 -
Rats have different biological make up compared with humans.
Different neuro-biology to humans
Carlsson
Mesolimbic pathway = positive symptoms
Mesocortic pathway = negative symptoms
L-dopa
Used to treat Parkinsons disease
Side effects - psychotic symptoms (similar to schizophrenia)