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Thyroid (Graves Disease (Symptoms (Irratability, Muscle weakness, Enlarged…
Thyroid
Hormones produced
T3
T4 (major) converted to T3
Calcitonin
Graves Disease
Autoimmune
Symptoms
Irratability
Muscle weakness
Enlarged thyroid (goitre)
Insomnia
Tachycardia
Unexplained weightloss
Thickening of the skins
Exopthalmus
Caused by TSI
acts on TSH receptor
No negative feedback
Diagnosis
Low TSH
T3/T4 High
Ultrasound scan
Physical examination
Treatment
Carbimazole
Propylthiouracil
B-Blockers eg. Propranolol
Radioiodine to kill thyroid cells
Surgical thyroidectomy
Other Hyperthyroidism
Drug induced
Amiodarone
Elevated T3/T4
Thyroid ademona
Thyrotoxicosis
Hypothyroidism
Primary
Gland unable to produce hormones
Physical damage
Drug induced
Secondary
Tumours
Surgery
Hashimotos
Autoimmune disease
Goitre
Genetic
High levels of TSH
Low levels of T3.T4
Treatment
Levothyroxine (T4)
Monitoring regularly (TFT)