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Alginate (Structure (Factors to consider when purchasing (G/M raTION, G…
Alginate
Structure
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Only the G blocks are believed to participate in intermolecular cross-linking with divalent cations :!:
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The mechanical properties are typically enhanced by increasing the length of G-block and the molecular weight
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Molecular weight
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The viscosity increases as pH decreases and reaches the maximum around pH 3-3.5
decrease in pH :arrow_right: increase in [H+] :arrow_right: COO- groups protonated :arrow_right: viscosity increase
The elastic modulus of gels can be increases (minimum increase in the viscosity) by combination of high and low molecular weight polymers
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Biocompatibility
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Impurities: heavy metals, endotoxins, proteins and polyphenolic compounds
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