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LUNG CANCER (background (3 types-細胞外觀 (NSCLC (非鱗狀NSCLC (adenocarcinomas肺腺癌…
LUNG CANCER
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treatment
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chemotherapy
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drug
targeted therapy
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ALK-1(kinase inhibitor)
Crizotinib
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AST/ALT↑, Bradyarrhythmia, QTinterval↑(可能永久停用)
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HER-2
Trastuzumab
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評估左心功能, Infusion reaction
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VEGF
Flt1 and KDR receptors
Bevacizumab
Proteinuria, Vaginal fistula, hypertension
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VEGF receptor2
Ramucirumab醫免
轉移性NSCLC, 接受platinum based療程後,再與併用docetaxel
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MEK1&2
Trametinib
BRAF V600E 突變,轉移性NSCLC,併用Dabrafenib
Rhabdomyolysis, Malignant melanoma
Retinal pigment epithelial detachmen
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chemo
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taxol
paclitaxel
nonPVC, 先給taxol再用cisplatin
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alopecia, mucous inflammatory
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Antimetabolites
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Pemetrexed-folate
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併用platinum
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febrile neutropenia, itching(dexa BID), B12?
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