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Hepatic Failure 2 (Chronic Liver Disease (the most common route to hepatic…
Hepatic Failure 2
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Ascites
accumulation of excessive fluid in the peritoneum cavity may reach 5-6 liters Because of hypoaglunemia so there will be different in the osmolarity
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Fetor hepaticus (musty” or “sweat & sour) bad breath smell due to Formation of mercaptans by action of GI bacteria on sulfur containing amino acid methionine & with P-S shunting to Lungs
Hyperammonemia because ammonia is detoxified mainly in the liver, when
the liver shutdown the ammonia will elevate
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Hyperestrogenemia palmar erythema (local vasodilatation) + spider angioma
- hypogonadism & gynecomastia in males
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Coagulopathy : impaired hepatic synthesis of clotting factors 10/9/7/2
Bleeding tendency & GI hemorrhage
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Hepatopulmonary syndrome : hypoxia, dyspnea, and cyanosis
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