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Anesthesia (Urethane [Ethyl carbamate] (articles (Ion Channels (how does…

- - - - Carbamic acid
  - - - U
        
        minimal effects on
        
        respiratory
        
        cardiovascular
        
        maintenance of spinal reflexes
        
        oocytes
        
        receptors
        
        AMPA
        
        glycine
        
        NAch
        
        GABAa
        
        N-methyl-D-aspartat
        
        in reversible and concentration-dependent manner
        
        EC50
        
        полумаксимальная эффективная концентрация
      - how does anesthetics works?
        
        enhance inhibition
        
        inhibit excitatory
        
        types
        
        Most anesthetics
        
        ketamine
        
        mainly NMDA
        
        volatile and IV
        
        U
        
        reversed the antagonistic
        effect of bicuculline on GABA-induced depolarization
    - - barrel cortex
        
        early ERPs
        
        peaks
        
        fast
        
        very fast
        
        gamma band
      - drugs
        
        urethane
        
        slowest responses
        
        propofol
        
        highest ampl
        
        ketamine/xylazine
        
        isoflurane
        
        nearly absent
        
        except for a very late component
        
        pentobarbital sodium
        
        states
        
        wake
        
        sleep