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Hirschsprung disease (Pathogenesis (Aganglionic
segment
(in rectum…
Hirschsprung disease
Pathogenesis
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because this aganglionic segment is not
going to relapse and not going to have peristaltic movement and this with time
leads to progressive dilatation and distention of the proximal colon which has
ganglionic cells (the proximal segment can relapse unlike the affected)
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more frequent in those with other congenital anomalies, like down
syndrome
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