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Regulation of sodium, potassium and water (Regulation of Na (Long term…
Regulation of sodium, potassium and water
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Regulation of potassium
Major ion intracellular, small amount in ECF
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Aldosterone
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Negative feedback Adrenal cortex detects -> more/less release aldosterone -> more/less K+ released in urine -> detected change in cortex
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Fluid compartments
- Neonates more "wet" than adults. About 80% total bm.
- Females slightly less than males
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Regulation of Na
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Excretion regulated by kidney
Affected by:
- GFR
- Reabsorption of Na from filtrate
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Long term
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Hydrostatic pressure (usually low) and oncotic pressure (usually high) in peritubular capillaries. Favour reabsorption but can change
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Natriuretic peptides (ANP, BNP & urodilatin)
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