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Sheep and Goat: Genetics and Biotechnology (Reproductive Technologies in…
Sheep and Goat: Genetics and Biotechnology
Reproductive Technologies in Sheep and Goats
Manipulation of breeding cycle (synching during oestrous)
Artificial insemination
Multiple ovulation and embryo transfer
Sexed semen
Breeding at younger ages
Reproductive cloning
Transgenesis
In vitro transformation and nuclear transfer (cloning)
Uses:
Modify existing genes
Introduce new genes for biomedical application
Knock in/out genes to investigate gene function or develop models for human disease
Genome editing
Biopharming
Mammary transgenesis vs Microbial systems
Easy collection and high protein expression
Microbial systems are used to produce transgenic proteins for human therapy
Mammary transgenic is believed to produce better products
Bioethics and Biotechnology
Concerns for unpredictable responses
Respect for nature
Animal welfare
Environmental safety