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Peptic Ulcer Disease (Duodenal ulcers are more frequent with (chronic…
Peptic Ulcer Disease
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Epidemiology
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all races, with little differences
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Pathogenesis:
Imbalance between the mucosal defenses
and the damaging forces ----> Mucosal
exposure to gastric acid and pepsin
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Chronic ulcers that occur in any portion of the
GIT exposed to the aggressive
action of acidic peptic juices
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Most often solitary, may be multiple
