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Barrett Esophagus (PATHOGENESIS (Prolonged and recurrent reflux,…
Barrett Esophagus
PATHOGENESIS
- Prolonged and recurrent reflux
- Inflammation and ulceration of the squamous
epithelium
- Healing and re-epithelization lead to columnar
mucosa (more resistant to gastric acid)
GROSS APPEARANCE
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Salmon-pink, velvety mucosa
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The replacement of the distal esophageal squamous mucosa by
metaplastic columnar epithelium above the level of LES
Gender: M:F is 4:1, race: common in white.
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