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Achalasia (THREE MAJOR ABNORMALITIES (Increased resting tone (persistent…

- - - - to overcome the
        obstruction and
        mechanical
        pressure
    - - ischemia, and mechanical
        pressure on the wall to
        accommodate all of the volume,
        which will form a sac-like structure
- - - - Autoimmunity,
      - previous viral infection
  - - - poliomyelitis
      - autonomic neuropathy in DM
    - - malignancy,
      - amyloidosis,
      - sarcoidosis.
    - - destruction of the
        myenteric plexus of the
        
        duodenum,
        
        colon,
        
        esophagus,
        
        ureter.