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Peptic Ulcer Disease-
a condition characterized by erosion of the GI…
Peptic Ulcer Disease-
a condition characterized by erosion of the GI mucosa from the digestive action of HCl acid and pepsin.
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Pathophysiology
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back diffusion of HCl acid into the gastric mucosa results in cellular destruction and inflammation.
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bloating, nausea, vomiting, and feeling of fullness
Epidemiology
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Any portion in of the GI tract in contact with gastric secretions is susceptible to ulcer development.
Risk Factors
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complications include hemorrhage, perforation, and gastric outlet obstruction
Treatment
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drug therapy
Proton Pump Inhibitors
Adverse effects- headache, diarrhea, nausea, rash, dizziness, osteoporosis
Histamine Receptors
Diarrhea, constipation, headache, fatigue, nausea, gynecomsatia, dry mouth, musculoskeletal pain
Antacids
Constipation, nausea, stomach cramps, fecal impaction, abdominal distention, belching, fluid retention
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