Juvenile Polyps and
Peutz-Jeghers Polyps
Hamartomatous proliferations of the lamina propria
In children younger < 5 years
Inflammation & ulceration are common
Large in children (1-3 cm) & small in adults
Juvenile polyposis
syndrome:
In adults called retention polyps
Sporadic
Pedunculated, smooth surfaced, reddish and display characteristic cystic spaces
Usually single in the rectum
No malignant potential
Multiple polyps.
May turn malignant
involve mucosal epithelium, lamina propria and muscularis mucosa
hamartomatous polyps
pedunculated with a lobulated contour
resemble a Christmas tree where they form an arborizing network of connective tissue
single or multiple polyps, multiple if
associated with a syndrome
Well-developed smooth muscle extends into the polyp and surrounds normal abundant glands
Hamartomatous proliferation of the lamina propria enclosing widely spaced dilated cystic glands
Inflammation and ulceration are common