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Aplastic Anaemia (Signs (No abnormal cells, uploaded image Hypocellular…
Aplastic Anaemia
Signs
No abnormal cells
Hypocellular bone marrow
No fibrosis
2/3 cell lines deficient (RBC, WBC, Plats)
Low reticulocytes
Fatty deposits visible
Causes
Radiation
Drug Induced (e.g. Chemo)
Viral
Idiopathic
Treatment
Blood Transfusion
Antibiotics
Immunosuppression (ciclosporin
Stem cell transplant
Complications
Risk of infection
Evolves to Paroxymal Nocturnal Haemoglobinuria
Evolves to acute leukaemia