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Disease of oral cavity (Fungal infections (Candidiasis (predesposing…
Disease of oral cavity
Fungal infections
Candidiasis
in the non-infectious stage is in the form of small yeast
once it
invades tissue it forms hyphae
The most common
are principally C. albicans
increas risk in
Presence of systemic disease
Tobaco smoking
Pregnancy
Denture wearers
is the most common oral fungal infection
predesposing factors
Systemic disease
Drugs
Xerostomia
extreme age
local factors
three major forms
Erythematous Candidiasis
in patients with iron-deficiency anemia or
in denture wearers
cause angular cheilitis
on the angles of the mouth and atrophy of the
tongue
atrophy of the mucosa
Hyperplastic Candidiasis (Candidal
Leukoplakia)
causes keratinization and appears
as a white patch
it’s pre-malignant
found in smokers in the buccal
mucosa
Pseudomembranous Candidiasis (Thrush)
superficial white cheese-like plaques
composed of hyphae enmeshed in fibrinopurulent exudate
most common form
scraped off
revealing an erythematous base,
In mildly immunosuppressed or debilitated individuals it remains superficial
in AIDS might go deep and need systemic anti-fungal drugs
AIDS
associated with different lesions in the oral cavity
Kaposi’s sarcoma
most common malignancy in AIDS patients caused by HSV8.
Hairy leukoplakia white
patches with hairy surface that are caused by
EBV on the lateral aspect of the
tongue
Herpetic vesicles
pseudomembranous Candidiasis the first sign for AIDS: