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Inflammatory and infectious lesions (Inflammatory and infectious lesions…
Inflammatory and infectious lesions
Inflammatory and infectious lesions
herpetic stomatitis
person suffers from a cold or becomes immunosuppressed
virus cause a secondary (recurrent) infection
, primary infection manifests as
primary herpetic gingivostomatitis
small vesicles can rupture and make ulcers all over the mouth and the gingiva becomes red and swallen
Virus enters proliferates then persist in the ganglia (trigeminal ganalia)
most common location for recurrence is the lip
herpic labialis
after primary infection in childhood
recurrent lesions occur at the site of primary inoculation or in adjacent
mucosa innervated by the same ganglion
herpes simplex infection
resolves in 7-10 days
In immunocompromised patients, it becomes chronic
may require systemic antiviral drugs
severe cases, this virus may seed the brain, causing
encephalitis or disseminated infection
the cells go acantholysis and float in the vesicle fluid
we call them tzanck cells
Adjacent cells may fuse to form multi nucliated gaint cells and we may see viral inclusions
infected cells undergo ballooning degeneration: swollen, eosinophilic
cytoplasm, pale vesicular nuclei