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Antivirals (olsetamivir(Tamiflu) zanamivir(Relenza) (Active against…
Antivirals
olsetamivir(Tamiflu) zanamivir(Relenza)
Active against Influenza A and B
Reduce duration of illness
Treatment within 2 days of symptoms
Tamiflu: causes N/V; PO only
Relenza: causes N/d, sinusitis
acyclovir (Zovirax)
Synthetic nucleoside analog
Supress replication of HSV-1, HSV-2, VZV
Drug of choice for recurrent episodes
Oral, topical, parenteral forms
ganciclovir (Cytovene)
Synthetic nucleoside analog
Used to treat CMV
Oral, parenteral forms
Toxicity: Bone marrow suppression
amantadine (Symmetrel)
Only treat Influenza A; not recommended
CNS effects
GI effects
rimantadine (Flumadine)
Only treat Influenza A
Less CNS effects
Cause GI upset