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RNA processing (tRNA (introns must be removed, 5' portion is removed…
RNA processing
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mRNA
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introns are removed
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an 3' adenine nucleotide attacks the 3' end of upstream exon, this causes the 5' end of the intron to be covalently linked to the A, the 3' free -OH group bonds with the 5' end of the next exon
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polyadenylation
transcription continues along the DNA until a polyadenylation consensus sequence (AATAAA) is found; this indicates cleavage of the mRNA ~ 20 nucleotides downstream (3')
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C-terminal domain (CTD): phosphorylation of the CTD ("tail" of RNA polymerase III) initiates elongation, it recruits molecules for capping, splicing, and 3' processing
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