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Diseases of the Salivary Glands (Tumors of the Salivary Glands (Malignant:…
Diseases of the Salivary Glands
Tumors of the Salivary Glands
Most of these neoplasms are benign: 70-80% of parotid tumors
Patients complain of mass at angle of jaw
80% of tumors occur in the parotid gland and it has M:F equal ratio in all ages
Benign:
pleomorphic adenoma
(AKA mixed tumor, most common
Recurrence 10%
heterogeneous histology with
epithelial elements, myxoid stroma (because of
the presence of myoepithelial cells), often
containing chondroid foci or, rarely, bone
Malignant transformation: 15% in
parotid, 40% in submandibular gland.
slowly growing, well-demarcated and
mostly arising from superficial parotid
not fully-encapsulated and has outgrowths,
has cysts that
can rupture during surgical removal, which can cause problems in conservative
removal in the parotid gland since the facial nerve passes through it.
Warthin’s tumor
benign slowly growing tumor
composed of cystic spaces lined by tall
columnar cells overlying abundant lymphoid tissue
AKA papillary cystadenoma lymphomatosum
vestigial embryonic remnants of branchial
cleft origin
Malignant:
carcinoma ex-pleomorphic adenoma
mucoepidermoid carcinoma (most common)
adenoid cystic carcinoma